None of these commands are available from the Start menu. However, msconfig can be opened from the address window.
I use Symantec AV, SpyBot S&D, AdAware, ZoneAlarm & Spyware Doctor. All with current definitions (checked for daily) so have a reasonably belief that my machine has not been compromised/invaded.
Have not recently installed or changed any programs, and have no idea how long this problem may have existed.