HiNorm, can't offer a permanent solution to your problem but I'm having the same happen. Did you buy your computer from the PC Co? Is your scanner an Acer? Yes to both questions for me and I continually have to uninstall and reinstall the scanner to get it to work. I can use it, then five minutes later try it again and get told it is cannot be detected. The first time it happened I checked all the cables and connections but all were fine. Annoying though it is, all I do now is uninstall and reinstall - a pain because if you are in the middle of something you have to close everything down and restart. If anyone knows how to fix it for good, I'd definitely be keen to hear from them.